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Preparation andor Purification of Oligonucleotide

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专利名称:Preparation and/or Purification of

Oligonucleotide Conjugates

发明人:David A. Schwartz,Leopoldo G. Mendoza申请号:US13578752申请日:20110211

公开号:US20130041140A1公开日:20130214

摘要:Methods, systems and/or kits for the preparation, purification and isolation ofoligonucleotide conjugates, comprising conjugation of modified antibodies or proteinswith at least one modified oligonucleotide at greater than 80% efficiency to formoligonucleotide conjugates and isolating the oligonucleotide conjugates from theconjugation solution by binding the conjugates to an immobilized binder, wherein thebinder may be a metal ion or an antibody.

申请人:David A. Schwartz,Leopoldo G. Mendoza

地址:Encinitas CA US,Scottsdale AR US

国籍:US,US

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