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PREPARATION ANDOR PURIFICATION OF OLIGONUCLEOTIDE

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专利名称:PREPARATION AND/OR PURIFICATION OF

OLIGONUCLEOTIDE CONJUGATES

发明人:SCHWARTZ, DAVID, A.,MENDOZA,

LEOPOLDO, G.

申请号:EP11742833申请日:20110211公开号:EP2534174A4公开日:20150225

摘要:Methods, systems and/or kits for the preparation, purification and isolation ofoligonucleotide conjugates, comprising conjugation of modified antibodies or proteinswith at least one modified oligonucleotide at greater than 80% efficiency to formoligonucleotide conjugates and isolating the oligonucleotide conjugates from theconjugation solution by binding the conjugates to an immobilized binder, wherein thebinder may be a metal ion or an antibody.

申请人:SOLULINK, INC.

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