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专利名称：Carboxamide derivatives and use thereof发明人：Yao, Jiangchao,Tafesse, Laykea申请号：AU2017204263申请日：20170623公开号：AU2017204263A1公开日：20170713
摘要：#$%^&*AU2017204263A120170713.pdf##### ABSTRACT The presentdisclosure provides substituted pyridyl-, pyrimidinyl-, pyrazinyl-, pyridazinyl-, andtriazinyl-based carboxamides of Formula I-A: R10 Z-HET-E I-A 5 and the pharmaceuticallyacceptable salts and solvates thereof, wherein Z, HET, R'0 , and E are defined as set forthin the specification. The present disclosure is also directed to the use of compounds ofFormula I-A to treat a disorder responsive to the blockade of sodium channels.Compounds of the present disclosure are especially useful for treating pain.
申请人：Purdue Pharma L.P.
代理人：FB Rice
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