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CARBOXAMIDE DERIVATIVES AND USE THEREOF

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专利名称:CARBOXAMIDE DERIVATIVES AND USE

THEREOF

发明人:YAO, Jiangchao,TAFESSE, Laykea申请号:EP14770495.1申请日:20140313公开号:EP2968307A4公开日:20170104

摘要:The present disclosure provides substituted pyridyl-, pyrimidinyl-, pyrazinyl-,pyridazinyl-, and triazinyl-based carboxamides of Formula I-A: R10 Z-HET-E I-A and thepharmaceutically acceptable salts and solvates thereof, wherein Z, HET, R10 and E aredefined as set forth in the specification. The present disclosure is also directed to the useof compounds of Formula I-A to treat a disorder responsive to the blockade of sodiumchannels. Compounds of the present disclosure are especially useful for treating pain.

申请人:Purdue Pharma LP

地址:One Stamford Forum 201 Tresser Boulevard Stamford, CT 06901 US

国籍:US

代理机构:Braun, Nils

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