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MODIFIED BACTERIAL PROTEIN EXPRESSION SYSTEM

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专利名称:MODIFIED BACTERIAL PROTEIN

EXPRESSION SYSTEM

发明人:GOTTESMAN, Maxwell申请号:EP168524.3申请日:20160928公开号:EP3356543A2公开日:20180808

摘要:The present disclosure provides host cells for reliable, high yield recombinantprotein production, including unstable proteins. The present host cell (e.g., a bacterialcell) is deficient in at least one protease (or a subunit of a protease) such as Clp or ClpP.The host cell may also contain an expression vector that encodes a protein orpolypeptide for overexpression.

申请人:The Trustees of Columbia University in the City of New York

地址:West 116th Street and Broadway New York, NY 10027 US

国籍:US

代理机构:FRKelly

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