专利内容由知识产权出版社提供
专利名称：GENE THERAPY FOR OCULAR
IMPROVEMENT
发明人：TARABORELLI, Donna,YOO,
Jesse,NORONHA, Glenn,COOPER, MarkJ.,MOEN, Robert C.,WHITE, Daniel
申请号：EP18883916申请日：20181128公开号：EP3717024A4公开日：20210825
摘要：Targeted non-surgical administration of a nucleic acid formulation to thesuprachoroidal space (SCS) of the eye of a human subject permits effective treatment ofocular disorders, including posterior ocular or choroidal maladies. In one embodiment,the method comprises inserting a hollow microneedle into the eye at an insertion siteand infusing a nucleic acid formulation through the inserted microneedle and into thesuprachoroidal space of the eye. The infused nucleic acid formulation flows within thesuprachoroidal space away from the insertion site. In one embodiment, the fluid nucleicacid formulation comprises nucleic acid nanoparticles consisting of one molecule ofnucleic acid.
申请人：Copernicus Therapeutics, Inc.,Clearside Biomedical, Inc.
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