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4-substituted azetidinones as precursors to 2-subs

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专利名称:4-substituted azetidinones as precursors to

2-substituted-3- carboxy carbapenemantibiotics and a method of producing them

发明人:Gregg Brian Feigelson,William V. Curran,Carl

Bernard Ziegler

申请号:US08/420955申请日:19950412公开号:US05700930A公开日:19971223

摘要:New 4-substituted azetidinones having the formulae I and II: ##STR1## whereinX is oxygen, sulfur or a moiety of the formula NR.sup.6 where R. sup.1, R.sup.2, R.sup.3,R.sup.4, R.sup.5 and R.sup.6 are defined hereafter, which are intermediates for thepreparation of carbapenem and carbacephem antibacterials and processes for producingsuch antibacterials through the utilization of an acid mediated ring closure reaction.

申请人:AMERICAN CYANAMID COMPANY

代理人:T. S. Szatkowski

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