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专利名称：1 Alkyl-4-(10:oxo or hydroxy-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5- ylidene)-piperidine compounds
发明人：John D. Prugh申请号：US05/280685申请日：19720814公开号：US03960872A公开日：19760601
摘要：The new 1-alkyl-4-(10-oxo or -hydroxy-10,11-dihydro-5H- dibenzo[a,d]
cyclohepten-5-ylidene)-piperidine compounds are prepared from the corresponding 10-desoxy compounds having a double bond at the 10, 11- position by a process involvingbromination, dehydrobromination of the resulting dibromo compound, followed byenamine formation and hydrolysis to give the desired 10-oxo compound. The compoundsprepared in this manner are active as antihistamines and as appetite stimulants.
申请人：MERCK & CO., INC.
代理人：Harry E. Westlake, Jr.,Thomas E. Arther,James A. Arno
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