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专利名称：EXPRESSION VECTOR FOR PRODUCTION OF
RECOMBINANT PROTEINS
发明人：GUNNAR NORSTEDT,TIM WOOD,DANIEL
SLIVA,BERTIL ENBERG,PETER LOBIE,LARS-ARNE HALDOSEN
申请号：US063288申请日：19971103
公开号：US200301920A1公开日：20031009
摘要：A method of enhancing the transcription of a gene in a DNA constructincorporated into the genome of a eucaryotic host cell, wherein the DNA constructcomprises a structural gene for a desired protein or polypeptide in a gene promoterupstream of the structural gene, comprises providing at least one enhancer elementcomprising the nucleotide sequence TTC TGA GAA upstream of the promoter, andexposing the DNA construct to lactogenic stimuli. An expression vector, a host cell and atransgenic mammal containing the vector are of interest.
申请人：NORSTEDT GUNNAR,WOOD TIM,SLIVA DANIEL,ENBERG BERTIL,LOBIEPETER,HALDOSEN LARS-ARNE
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