Product Data SheetProduct Name:CAS No.: Cat. No.:MWt:Formula:Purity :Methscopolamine bromide155-41-9HY-B0344398.29C18H24BrNO4>98%Solubility:DMSO 80 mg/mL; Water 80 mg/mLMechanisms: Pathways:GPCR/G protein; Target:mAChR Pathways:Neuronal Signaling; Target:mAChR Biological Activity:Methscopolamine (Pamine) is a muscarinic acetylcholine receptor blocker. Methscopolamine(Pamine)isamuscarinicacetylcholinereceptorblockerTarget: mAChR Methylscopolamine is an oral medication used along with other medications to treat peptic ulcers byreducing stomach acid secretion. With the advent of proton pump inhibitors and antihistaminemedications it is rarely used for this. It can also be used for stomach or intestinal spasms, to reducesalivation, and to treat motion sickness. From Wikipedia. Methscopolamine (Pamine), an anti-acetylcholine drug, prevented ulcer formation, reduced furthervolume and acid output but produced a 3-4 fold increase in hexosamine concentration. Tissue(corpus and antrum) hexosamine was moderately reduced by restraint. In the corpus, this wascounteracted by methscopolamine but antrum hexosamine was not influenced by this drug. The anti-ulcer property of methscopolamine may be due not only to its...References:[1]. Robert, A. and J.E. Nezamis, Effect of an Anti-Acetylcholine Drug, Methscopolamine Bromide,on Ulcer Formation and Gastric Mucus. J Pharm Pharmacol, 19. 16: p. 690-5. Caution: Not fully tested. For research purposes onlyMedchemexpress LLCwww.medchemexpress.com18Wilkinson Way, Princeton, NJ 08540,USAEmail: info@medchemexpress.com Web: www.medchemexpress.com
