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THIOXANTHINE DERIVATIVES AND THEIR USE AS INHIBITO

来源:化拓教育网
专利内容由知识产权出版社提供

专利名称:THIOXANTHINE DERIVATIVES AND THEIR

USE AS INHIBITORS OF MPO

发明人:TIDEN, ANNA-KARIN,VIKLUND, JENNY申请号:EP07748015申请日:20070412公开号:EP2010535A4公开日:20110720

摘要:There are disclosed novel compounds of Formula (I) wherein L, R1, X and Y areas defined in the specification, and pharmaceutically acceptable salts thereof; togetherwith processes for their preparation, compositions containing them and their use intherapy. The compounds are inhibitors of the enzyme MPO and are thereby particularlyuseful in the treatment or prophylaxis of neuroinflammatory disorders, cardio- andcerebrovascular atherosclerotic disorders and peripheral artery disease and respiratorydisorders.

申请人:ASTRAZENECA AB

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