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专利名称：Novel autoinducer molecules and uses
therefor
发明人：EVERETT C PESCI,JARED B J MILBANK,JAMES
P. PEARSON,ANDREW S. KENDE,EVERETTPETER GREENBERG,BARBARA H. IGLEWSKI
申请号：AU8697601申请日：20010831公开号：AU8697601A公开日：20020313
摘要：Novel bacterial quinolone signal molecules and, more particularly,
pseudomonas quinolone signal (\"PQS\") molecules, e.g., 2-heptyl-3-hydroxy-4-quinolone,and analogs and derivatives thereof are described. Therapeutic compositions containingthe molecules, and therapeutic methods, methods of for regulating gene expression,methods for identifying modulators of the autoinducer molecules, and methods ofmodulating quorum sensing signaling in bacteria using the compounds of the inventionare also described.
申请人：THE UNIVERSITY OF IOWA RESEARCH FOUNDATION,EAST CAROLINAUNIVERSITY,UNIVERSITY OF ROCHESTER
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